Substrate: Histone deacetylase 1 (Cell cycle control protein)
Seq-ID: O09106 [Mus musculus]
Download:fasta csv
Interaction Network(s): STRING  
External Source(s): PhosidaPhosida
MINT Interaction(s):
MINT-2568200   TAL1_MOUSE
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
histone deacetylase activity,
transcription corepressor activity,
chromatin binding,
sequence-specific DNA binding transcription factor activity		 neuronal cell body,
cytoplasm,
NuRD complex,
heterochromatin		 negative regulation of gene-specific transcription from RNA polymerase II promoter,
hippocampus development,
transcription,
endoderm development,
neuron differentiation
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 393 AIPEDAIPEESGDEDEEDPDK - 19144319
HTP
0.21
 - -
0.89
 - medium
S 421 DKRIACEEEFSDSDEEGEGGR - 19144319
HTP
0.36
 - -
0.74
 - medium
S 423 RIACEEEFSDSDEEGEGGRKN - 19144319
HTP
0.49
 - -
0.76
 - medium

Substrate: Histone deacetylase 1 (Cell cycle control protein)
Seq-ID: Q13547 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-49667   SP1_HUMAN
MINT-50169   NFKB1_HUMAN
MINT-50171   TF65_HUMAN
MINT-73393   VE7_HPV16
MINT-1957407   HIF1A_HUMAN
MINT-1957435   MTA1_HUMAN
MINT-4303210   DHX30_HUMAN
MINT-4303486   NR2E3_HUMAN
MINT-4303628   RBBP7_HUMAN
MINT-4544899   NPM_HUMAN
MINT-6628404   RB_HUMAN
MINT-6628780   LT_SV40
MINT-6823807   CTNB1_HUMAN
MINT-7302173   BUB1B_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
identical protein binding,
specific transcriptional repressor activity,
transcription activator activity,
histone deacetylase activity,
histone deacetylase binding,
transcription factor binding,
sequence-specific DNA binding transcription factor activity		 Sin3 complex,
cytosol,
NuRD complex		 negative regulation of gene-specific transcription from RNA polymerase II promoter,
positive regulation of cell proliferation,
positive regulation of gene-specific transcription from RNA polymerase II promoter,
transcription,
negative regulation by host of viral transcription,
histone H4 deacetylation,
anti-apoptosis,
histone H3 deacetylation,
positive regulation of receptor biosynthetic process,
chromatin remodeling,
negative regulation of cell cycle
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 393 AIPEDAIPEESGDEDEDDPDK - 17081983
HTP
0.22
 - -
0.89
 - medium
S 393 AIPEDAIPEESGDEDEDDPDK - 18669648
HTP
0.22
 - -
0.89
 - medium
S 406 EDEDDPDKRISICSSDKRIAC - 18669648
HTP
0.45
 - -
0.60
 - medium
S 409 DDPDKRISICSSDKRIACEEE - 18669648
HTP
0.17
 - -
0.53
 - medium
S 410 DPDKRISICSSDKRIACEEEF - 18669648
HTP
0.09
 - -
0.51
 - medium
S 421 DKRIACEEEFSDSEEEGEGGR CK2_group 11602581
LTP
0.35
 MOD_CK2_1
 - -
0.73
 - medium
S 421 DKRIACEEEFSDSEEEGEGGR CK2_alpha 11602581
LTP
0.35
 MOD_CK2_1
 - -
0.73
 - medium
S 421 DKRIACEEEFSDSEEEGEGGR - 17081983
HTP
0.35
 MOD_CK2_1
 - -
0.73
 - medium
S 421 DKRIACEEEFSDSEEEGEGGR - 17287340
HTP
0.35
 MOD_CK2_1
 - -
0.73
 - medium
S 421 DKRIACEEEFSDSEEEGEGGR - 18669648
HTP
0.35
 MOD_CK2_1
 - -
0.73
 - medium
S 423 RIACEEEFSDSEEEGEGGRKN CK2_group 11602581
LTP
0.42
 MOD_CK2_1
 - -
0.76
 - medium
S 423 RIACEEEFSDSEEEGEGGRKN CK2_alpha 11602581
LTP
0.42
 MOD_CK2_1
 - -
0.76
 - medium
S 423 RIACEEEFSDSEEEGEGGRKN - 17081983
HTP
0.42
 MOD_CK2_1
 - -
0.76
 - medium
S 423 RIACEEEFSDSEEEGEGGRKN - 17287340
HTP
0.42
 MOD_CK2_1
 - -
0.76
 - medium
S 423 RIACEEEFSDSEEEGEGGRKN - 18669648
HTP
0.42
 MOD_CK2_1
 - -
0.76
 - medium

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